The beautiful garden in Eden which God created for our first parents was complete, perfect.  In it and through it He gave them everything they needed including a vocation, that noble work to tend it.  When they thought they knew better than God what they needed, they lost it all, including the beauty and fulfillment of their calling.  Consequently, their work, and that of their descendants, became more difficult.  God still calls all to their vocations, but His followers can only work with hope because their Savior fulfilled His calling and is preparing a new home for them.